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Senescence is a process in which ageing cells stop dividing and is involved in many diseases of ageing. Over time senescent cells build up in tissues and release harmful substances causing inflammation and damage to healthy cells. The development of OA correlates with a rise in the number of senescent cells in joint tissues.

Laboratory studies at INIBIC (Instituto de Investigación Biomédica de A Coruña) have demonstrated APPA’s senolytic and senomorphic properties. A new patent application has been filed covering APPA’s senomorphic effects in a wide range of age-related conditions.

This patent application, if granted, will complement APPA’s existing patent family (composition and improved formulation) and will further extend APPA’s patent life.